Candice Accola: I Don’t Think Caroline and Tyler's Relationship Can Recover

• Are Caroline and Tyler over for good? And is there even hope for a friendship?

Although Tyler was the one to walk away from the relationship, Caroline committed the ultimate act of betrayal by sleeping with his mortal enemy, Klaus. With the cat out of the bag, and Tyler sure that he wants nothing to do with her, Caroline walked into this episode's Bitter Ball and shredded remnants of both men.

But does Caroline ever remain single for very long? Although there were hints of jealousy over watching Stefan and Elena/Katherine dance, Accola tells TVGuide.com that those two are destined for great friendship.

What´s with Caroline and Stefan?

Spoiler Alert

Caroline turns out to be pretty jealous of Stefan and the new "relation" he has with Elena. Julie Plec said: "Caroline and Stefan are big friends and they are gonna continue with this beautiful friendship. We´ll see if something more happens or if they continue in their own directions."

EXTENDED PROMO OF "THE DEVIL INSIDE" (#5.12)

PROMO OF "THE DEVIL INSIDE" (#5.12)

"Things are going to get really tricky (...)" - Julie Plec, Exclusive Interview.

• SPOILER! --> If you haven´t seen Episode 100, 500 Years Of Solitude (#5.11) don´t read this.

Katherine Pierce spent the majority of the episode, "500 Years of Solitude," lying on her deathbed believing her end was near. In celebration of her impending doom, Damon, Stefan and Co. took shots as they reminisced about the terrible things Katherine has done since season one. But after Nadia introduced a Plan B for how Katherine could skirt death, she jumped at the chance. By the end of the hour, Katherine took over Elena's body -- but only Nadia is in on the plan. R.I.P. Elena?

The episode also featured a long list of cameos, listed here in order of appearance:

1. Sheriff Forbes (Marguerite MacIntyre), 
2. Klaus (Joseph Morgan), 
3. Emily Bennett (Bianca Lawson), 
4. Rebekah (Claire Holt), 
5. Aunt Jenna (Sarah Canning), 
6. Uncle John (David Anders), 
7. Elijah (Daniel Gillies), 
8. Vicki (Kayla Ewell), 
9. Tyler (Michael Trevino),
10. Alaric (Matt Davis).

Julie Plec talks to THR about the episode's memorable returns and that shocking Katherine/Elena body-snatch in the final minutes.

The 100th episode featured a ton of cameos, including characters we haven't seen in a while. Since you couldn't feature everyone who made an impact, what were the guidelines with who would appear?

We knew we wanted to bring back everybody that had ever been a series regular for part of our family long-term. On top of that, we just love shouting back to little things, little characters, over the course of the series that were either embedded in the story or had great moments like the Uncle John moment [in season one] or Emily Bennett who, of course, was Katherine's sidekick back in the day.  

The opening was quite comedic, with the major characters reminiscing about Katherine.  How did you want to open this particular episode?

In the beginning, we're reminding the audience that Katherine used to just be a human girl who accidentally got pregnant -- and losing that baby, or having it taken away from her, was the catalyst for the rest of her life and the very thing that turned her into the person that she is. Coming off something so intense and learning that she's going to die, we loved that idea of kicking off the episode with what felt like a celebration.

It was also one of the rare moments where you had a lot of the major players in the same room.

Let me tell you, it takes some time to shoot when you get more than four people in a room too.

STILLS OF: "The Devil Inside" (#5.12)

SYNOPSIS: The Devil Inside (#5.12)

• Official Synopsis (#5.12) --> The Devil Inside

SEARCHING FOR THE HIGH ROAD - When Enzo brings Damon a gruesome present and insists that they bond by committing an act of revenge, Damon makes an effort to do the honorable thing. After finding himself in awkward and confusing conversations with Nadia, Matt impulsively decides to throw a party, where Caroline makes a stunning confession to Elena, then has to face the consequence of her actions with Stefan and Tyler. Aaron does his best to make amends for his family's past misdeeds and start a new life for himself. Finally, Elena suddenly finds herself in a life-threatening situation with only minutes to figure out how to save herself.